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Dr. Schrage has a BS in Biology from University of Utah, and PhD from University of Missouri-Columbia. He completed a postdoctoral fellowship at the Mayo Clinic in Rochester, MN before arriving in Madison in 2006. His teaching covers undergraduate and graduate classes in Kinesiology, mainly around environmental and exercise physiology. He serves on numerous departmental,
School of Education, and National Scientific commitees. Dr. Schrage leads a laboratory focused on how blood flow is regulated to different organs, how control changes with obesity and prediabetes, and test whether biological sex impacts cardiovascular and blood flow control in health and disease. They test these ideas directly in human volunteers, using a range of non-invasive and invasive approaches including state-of-the-art MRI. The lab has been funded by National Institutes of Health, American Heart Association, and American Diabetes Association.
Education
- Postdoctoral Integrative Human Physiology, Mayo Clinic, 2006
- PhD Physiology, University of Missouri, 2001
- Postdoctoral Veterinary Biomedical Science, University of Missouri, 2001
- MS Exercise Physiology, University of Utah, 1994
- BS Biology, University of Utah, 1991
Select Publications
- Carter, K. J., Ward, A. T., Kellawan, J. M., Eldridge, M., Al-Subu, A., Walker, B. J., Lee, J. W., Wieben, & Schrage, W. G. (2021). Nitric oxide synthase inhibition in healthy adults reduces regional and total cerebral macrovascular blood flow and microvascular perfusion. J Physiol
- Harrell, J. W., Peltonen, G. L., & Schrage, 1. G. (2019). Reactive oxygen species and cyclooxygenase products explain the majority of hypoxic cerebral vasodilation in healthy humans. Acto PHysiol, 226(4)
- Hoscheidt, S. M., Kellewan, M., Berman, S. E., Rivera-Rivera, L. A., Krause, R. A., Oh, J. M., Beeri, M. S., Rowley, H. A., Wieben, O., Carlsson, C. M., Asthana, S., Johnson, S. C., Schrage, W. G., & Bendlin, B. B. (2017). Insulin resistance is associated with lower arterial blood flow and reduced cortical perfusion in cognitively asymptomatic middle-aged adults. Journal of Cerebral Blood Flow Metabolism, 37(6), 2249-2261.
- Limberg, J. K., Morgan, B. J., & Schrage, W. G. (2016). Peripheral Blood Flow Regulation in Human Obesity and Metabolic Syndrome. Exercise Sport Science Reviews, 44(3), 116-122.
- Limberg, J. K., Peltonen, G. L., Johansson, R. E., Harrell, J. W., Kellewan, M., Eldridge, M. W., Sebranek, J. J., Walker, B. J., & Schrage, W. G. (2016). Greater Beta-Adrenergic Receptor Mediated Vasodilation in Women Using Oral Contraceptives.. Frontiers in Physiology, 7, 215.
- Peltonen, G. L., Harrell, J. W., Aleckson, B. P., LaPlante, K. M., Crain, M., & Schrage, W. G. (2016). Cerebral blood flow regulation in women across menstrual phase: differential contribution of cyclooxygenase to basal, hypoxic, and hypercapnic vascular tone.. , ajpregu.00106.2016. American journal of physiology. Regulatory, integrative and comparative physiology.
- Peltonen, G. L., Harrell, J. W., Rousseau, C. L., Ernst, B. S., Marino, M. L., Crain, M., & Schrage, W. G. (2015). Cerebrovascular regulation in men and women: stimulus-specific role of cyclooxygenase.. Physiological Reports
- Kellawan, J. M., Johansson, R. E., Harrell, J. W., Sebranek, J. J., Walker, B. J., Eldridge, M. W., & Schrage, W. G. (2015). Exercise vasodilation is greater in women: contributions of nitric oxide synthase and cyclooxygenase.. European Journal of Applied Physiology
- Limberg, J. K., Kellawan, J. M., Harrell, J. W., Johansson, R. E., Eldridge, M. W., Proctor, L. T., Sebranek, J. J., & Schrage, W. G. (2014). Exercise-mediated vasodilation in human obesity and metabolic syndrome: effect of acute ascorbic acid infusion.. American Journal of Physiology. Heart and circulatory physiology
- Blain, G. M., Limberg, J. K., Mortenson, G. F., & Schrage, W. G. (2012). Rapid onset vasodilation is blunted in obese humans. Acta Physiologica, 1408-1416.
Select Presentations
- Schrage, W. G. (2020, February). Cerebral blood flow regulation during environmental stress: Impact of insulin resistance. presented at the , Iowa City, IA.
- Schrage, W. G. (2017). Cerebrovascular Control is Challenged by Insulin Resistance. Oral Presentation presented at the Symposium: Deranged Cardiovascular Stress Responses in Individuals with Insulin Resistance, Denver, CO.
- Schrage, W. G. (2016, October). Controlling muscle blood flow in obese humans. Seminar presented at the Department Seminar, York University, Toronto, Ontario, Canada..
- Schrage, W. G. (2016, August). Cerebral blood flow during stress: impact of insulin resistance. Oral Presentation presented at the , University of Birmingham, UK.
- Schrage, W. G. (2014, September). Blood flow control during exercise in obesity and metabolic syndrome. Oral Presentation presented at the Symposium: "Exercise and Vascular Health", Miami, FL.
- Schrage, W. G. (2010, June). Regulation of muscle blood flow in obesity. Oral Presentation presented at the American College of Sports Medicine National Meeting, Baltimore, MD.
- Schrage, W. G. (2010, January). Vascular control in obese humans. Seminar presented at the Invited Talk, Salt Lake City, UT.
- Schrage, W. G. (2009, November). Regulation of muscle blood flow in obese humans. Seminar presented at the Invited talk to Noll Laboratory, State College, PA.
Select Awards and Honors
- Fellow, American Physiological Society, 2018
- First alternate to New Zealand, American Physiological Society, 2018
- Vilas Research Associate, UW-Madison Vilas Foundation, (2015, 2017)
- Gail Patrick Innovation Award, American Diabetes Association, 2013
- LRP Clinical Research Award, National Institutes of Health, (2003, 2007)
- Environmental & Exercise Physiology Recognition Award, American Physiological Society, 2004
- Research Team Member, Space Shuttle Columbia (STS-107), FRESH Project, 2003